University of California San Francisco

Lucas Wachsmuth, MD, PhD

Lucas Wachsmuth
Lucas Wachsmuth, MD, PhD

Resident (PGY-1)
General Surgery

    Education

    Institution Degree Dept or School End Date
    Duke University MD, PhD Tumor Immunology 05/2025
    University of Georgia BS Biochemistry, Biology 05/2014

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 16
    1. Antigen presentation by tumor-associated macrophages drives T cells from a progenitor exhaustion state to terminal exhaustion.
      Waibl Polania J, Hoyt-Miggelbrink A, Tomaszewski WH, Wachsmuth LP, Lorrey SJ, Wilkinson DS, Lerner E, Woroniecka K, Finlay JB, Ayasoufi K, Fecci PE| | PubMed
    2. Combination checkpoint blockade and laser interstitial thermal therapy in radiographically progressive non-small cell lung cancer brain metastases.
      Haskell-Mendoza AP, Srinivasan ES, Gonzalez AT, Reason EH, Jackson JD, Flusche AM, Wachsmuth LP, Lerner E, Underwood D, Buckley ED, Zaidi SE, Herndon JE, Fecci PE| | PubMed
    3. The LITT Fit in neuro-oncology: indications, imaging, and adjunctive therapies.
      Haskell-Mendoza AP, Gonzalez AT, Reason EH, Flusche AM, Chongsathidkiet P, Wachsmuth LP, Goodwin CR, Fecci PE| | PubMed
    4. Gold Nanostars Obviate Limitations to Laser Interstitial Thermal Therapy (LITT) for the Treatment of Intracranial Tumors.
      Srinivasan ES, Liu Y, Odion RA, Chongsathidkiet P, Wachsmuth LP, Haskell-Mendoza AP, Edwards RM, Canning AJ, Willoughby G, Hinton J, Norton SJ, Lascola CD, Maccarini PF, Mariani CL, Vo-Dinh T, Fecci PE| | PubMed
    5. CD8+ T cells maintain killing of MHC-I-negative tumor cells through the NKG2D-NKG2DL axis.
      Lerner EC, Woroniecka KI, D'Anniballe VM, Wilkinson DS, Mohan AA, Lorrey SJ, Waibl-Polania J, Wachsmuth LP, Miggelbrink AM, Jackson JD, Cui X, Raj JA, Tomaszewski WH, Cook SL, Sampson JH, Patel AP, Khasraw M, Gunn MD, Fecci PE| | PubMed
    6. Foxn1 overexpression promotes thymic epithelial progenitor cell proliferation and mTEC maintenance, but does not prevent thymic involution.
      Li J, Wachsmuth LP, Xiao S, Condie BG, Manley NR| | PubMed
    7. Posttransplantation cyclophosphamide expands functional myeloid-derived suppressor cells and indirectly influences Tregs.
      Fletcher RE, Nunes NS, Patterson MT, Vinod N, Khan SM, Mendu SK, Li X, de Paula Pohl A, Wachsmuth LP, Choo-Wosoba H, Eckhaus MA, Venzon DJ, Kanakry CG| | PubMed
    8. Systemic immune derangements are shared across various CNS pathologies and reflect novel mechanisms of immune privilege.
      Lorrey SJ, Waibl Polania J, Wachsmuth LP, Hoyt-Miggelbrink A, Tritz ZP, Edwards R, Wolf DM, Johnson AJ, Fecci PE, Ayasoufi K| | PubMed
    9. Erratum to "E.C. Lerner, E.S. Srinivasan, G. Broadwater, et al. Factors Associated With New-Onset Seizures Following Stereotactic Radiosurgery for Newly Diagnosed Brain Metastases. Adv Radiat Oncol. 2022;7:101054."
      Lerner EC, Srinivasan ES, Broadwater G, Haskell-Mendoza AP, Vaios EJ, Edwards RM, Wachsmuth LP, Huie D, Floyd SR, Adamson JD, Fecci PE| | PubMed
    10. Efflux capacity and aldehyde dehydrogenase both contribute to CD8+ T-cell resistance to posttransplant cyclophosphamide.
      Patterson MT, Nunes NS, Wachsmuth LP, Panjabi A, Fletcher RE, Khan SM, Dimitrova D, Kanakry JA, Luznik L, Kanakry CG| | PubMed
    11. Grief in Medical Students: The Short and Long-Term Impacts on Health and Well-Being.
      Price MJ, Wachsmuth LP, Ferguson KA, Robbins-Welty GA, Riordan PA, Pieper CF, Galanos A| | PubMed
    12. Hepatic vascular malignancies in children are associated with increased rates of surgical resection and improved overall survival compared with adults.
      Commander SJ, Cerullo M, Leraas HJ, Reed CR, Achey MA, Wachsmuth LP, Schooler GR, Tracy ET| | PubMed
    13. Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation.
      Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Kanakry CG| | PubMed
    14. Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.
      Wachsmuth LP, Patterson MT, Eckhaus MA, Venzon DJ, Gress RE, Kanakry CG| | PubMed
    15. Do Biology Students Really Hate Math? Empirical Insights into Undergraduate Life Science Majors' Emotions about Mathematics.
      Wachsmuth LP, Runyon CR, Drake JM, Dolan EL| | PubMed
    16. The Ty1 Retrotransposon Restriction Factor p22 Targets Gag.
      Tucker JM, Larango ME, Wachsmuth LP, Kannan N, Garfinkel DJ| | PubMed